hyperscope multiphoton system Search Results


hyperscope multiphoton imaging system  (Scientifica)
86
Scientifica hyperscope multiphoton imaging system
Hyperscope Multiphoton Imaging System, supplied by Scientifica, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/hyperscope+multiphoton+system/hyperscope+scientifica/bio_rxiv__64898__2026__03__04__709616-248-8-12
Average 86 stars, based on 1 article reviews
hyperscope multiphoton imaging system - by Bioz Stars, 2026-11
86/100 stars
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multiphoton microscope  (Scientifica)
86
Scientifica multiphoton microscope
Multiphoton Microscope, supplied by Scientifica, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/hyperscope+multiphoton+system/microscope+multiphoton/pm41896245-410-5-8
Average 86 stars, based on 1 article reviews
multiphoton microscope - by Bioz Stars, 2026-11
86/100 stars
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multiphoton system  (Coherent Corp)
99
Coherent Corp multiphoton system
FUS-16R causes the formation of dendritic inclusions which exhibit spontaneous movement that is enhanced by neuronal activity . A Representative confocal images illustrating the somatic and dendritic region of CA1 neurons expressing either FUS-16R-EYFP (FUS-16R) and td-tomato (top panels; cell 1–4) or FUS-WT-EYFP (FUS-WT) and td-tomato (bottom panels; cell 5–8). B Representative straightened time-lapse image of an apical dendritic region transfected with FUS-16R top panel (1 s), middle panel (6 s). Live imaging allowed for the tracking of individual FUS-16R condensates as indicated by the pseudo-colour merged time-lapse image (bottom panel; green 1 s; magenta 6 s). C Quantification of the FUS-16R-EYFP granule trajectory length recorded from individual granules. D Representative pseudo-coloured heat map of FUS16R condensate intensity in a dendritic region of interest. Dendritic FUS16R condensates are highlighted (ROI1-3) and their movement trajectory over a 1-min period is plotted for pre-stimulation (baseline; black line) and post-stimulation (Chrismon depolarisation; red line). E Quantification of normalised FUS-16R-condensate movement (averaged 5–6 ROIs per cell, n = 6). Average trajectory length was longer post-stimulation (p = 0.009373, paired t-test). F Representative <t>multiphoton</t> timelapse (10-min interval) heat maps of FUS-16R intensity at a single CA1 dendritic spine prior to and following single spine glutamate uncaging. A single spine was stimulated (cyan dot) and the FUS-16R intensity was measured by line scan across spine head. Histogram (below) illustrating FUS-16R condensate signal following stimulation in the presence (red bars) and absences (grey bars) of MNI-glutamate. Stimulation in the presence of MNI-glutamate significantly increased condensate signal at 20- (p = 0.0485, post hoc Tukey) and 30-min (p = 0.0214, post hoc Tukey) post-stimulation. **p < 0.01, paired t-test
Multiphoton System, supplied by Coherent Corp, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/hyperscope+multiphoton+system/Chameleon/pmc10726623-242-19-25
Average 99 stars, based on 1 article reviews
multiphoton system - by Bioz Stars, 2026-11
99/100 stars
  Buy from Supplier

Image Search Results


FUS-16R causes the formation of dendritic inclusions which exhibit spontaneous movement that is enhanced by neuronal activity . A Representative confocal images illustrating the somatic and dendritic region of CA1 neurons expressing either FUS-16R-EYFP (FUS-16R) and td-tomato (top panels; cell 1–4) or FUS-WT-EYFP (FUS-WT) and td-tomato (bottom panels; cell 5–8). B Representative straightened time-lapse image of an apical dendritic region transfected with FUS-16R top panel (1 s), middle panel (6 s). Live imaging allowed for the tracking of individual FUS-16R condensates as indicated by the pseudo-colour merged time-lapse image (bottom panel; green 1 s; magenta 6 s). C Quantification of the FUS-16R-EYFP granule trajectory length recorded from individual granules. D Representative pseudo-coloured heat map of FUS16R condensate intensity in a dendritic region of interest. Dendritic FUS16R condensates are highlighted (ROI1-3) and their movement trajectory over a 1-min period is plotted for pre-stimulation (baseline; black line) and post-stimulation (Chrismon depolarisation; red line). E Quantification of normalised FUS-16R-condensate movement (averaged 5–6 ROIs per cell, n = 6). Average trajectory length was longer post-stimulation (p = 0.009373, paired t-test). F Representative multiphoton timelapse (10-min interval) heat maps of FUS-16R intensity at a single CA1 dendritic spine prior to and following single spine glutamate uncaging. A single spine was stimulated (cyan dot) and the FUS-16R intensity was measured by line scan across spine head. Histogram (below) illustrating FUS-16R condensate signal following stimulation in the presence (red bars) and absences (grey bars) of MNI-glutamate. Stimulation in the presence of MNI-glutamate significantly increased condensate signal at 20- (p = 0.0485, post hoc Tukey) and 30-min (p = 0.0214, post hoc Tukey) post-stimulation. **p < 0.01, paired t-test

Journal: Acta Neuropathologica Communications

Article Title: Mimicking hypomethylation of FUS requires liquid–liquid phase separation to induce synaptic dysfunctions

doi: 10.1186/s40478-023-01703-w

Figure Lengend Snippet: FUS-16R causes the formation of dendritic inclusions which exhibit spontaneous movement that is enhanced by neuronal activity . A Representative confocal images illustrating the somatic and dendritic region of CA1 neurons expressing either FUS-16R-EYFP (FUS-16R) and td-tomato (top panels; cell 1–4) or FUS-WT-EYFP (FUS-WT) and td-tomato (bottom panels; cell 5–8). B Representative straightened time-lapse image of an apical dendritic region transfected with FUS-16R top panel (1 s), middle panel (6 s). Live imaging allowed for the tracking of individual FUS-16R condensates as indicated by the pseudo-colour merged time-lapse image (bottom panel; green 1 s; magenta 6 s). C Quantification of the FUS-16R-EYFP granule trajectory length recorded from individual granules. D Representative pseudo-coloured heat map of FUS16R condensate intensity in a dendritic region of interest. Dendritic FUS16R condensates are highlighted (ROI1-3) and their movement trajectory over a 1-min period is plotted for pre-stimulation (baseline; black line) and post-stimulation (Chrismon depolarisation; red line). E Quantification of normalised FUS-16R-condensate movement (averaged 5–6 ROIs per cell, n = 6). Average trajectory length was longer post-stimulation (p = 0.009373, paired t-test). F Representative multiphoton timelapse (10-min interval) heat maps of FUS-16R intensity at a single CA1 dendritic spine prior to and following single spine glutamate uncaging. A single spine was stimulated (cyan dot) and the FUS-16R intensity was measured by line scan across spine head. Histogram (below) illustrating FUS-16R condensate signal following stimulation in the presence (red bars) and absences (grey bars) of MNI-glutamate. Stimulation in the presence of MNI-glutamate significantly increased condensate signal at 20- (p = 0.0485, post hoc Tukey) and 30-min (p = 0.0214, post hoc Tukey) post-stimulation. **p < 0.01, paired t-test

Article Snippet: Organotypic slices were submerged in a low Mg 2+ HEPES buffer and images acquired at room temperature on a multiphoton system (Scientifica Hyperscope with a Coherent Chameleon Discovery; Nikon 16x, 0.8 NA lens or a Nikon 25x, 1.1 NA lens).

Techniques: Activity Assay, Expressing, Transfection, Imaging